The three-part documentary "The One About Matthew Perry" explores the actor's career, addiction challenges, and 2023 death from ketamine-related drowning, according to TheWrap. It features testimony from his sister Mia Perry Bowick and lifelong friends who describe his complex personality and struggles.

Mia Perry Bowick, Matthew Perry's sister, spoke publicly for the first time about her brother's life and legacy in the documentary. She emphasized seeing him as a whole person beyond his "Friends" character or addiction struggles, as reported by Netflix's Tudum publication.